Key Takeaways
- Novo Nordisk (NVO) and Eli Lilly (LLY) collectively saw their market capitalization plummet by $250 billion on Friday, driven by investor weariness over the weight-loss drug market and threats from former President Donald Trump regarding pharmaceutical tariffs.
- A previously planned one-on-one meeting between President Donald Trump and Russian President Vladimir Putin has been expanded to a three-on-three format.
- President Trump is joined by Secretary of State Marco Rubio and Special Envoy Steve Witkoff for the expanded bilateral meeting in Anchorage, Alaska.
- Trump's threats to the pharmaceutical industry include potential tariffs of up to 250% on drug imports and demands for drugmakers to align U.S. prices with cheaper European levels.
Novo Nordisk (NVO) and Eli Lilly (LLY), two pharmaceutical titans, experienced a massive $250 billion wipeout in market value on Friday. The significant decline was attributed to a combination of growing investor skepticism regarding the long-term growth trajectory of the weight-loss drug market and heightened threats from former President Donald Trump concerning pharmaceutical pricing and imports.
The market's "weight-loss weariness" stems from increasing competition within the GLP-1 drug sector, including the rise of compounding pharmacies offering cheaper, unofficial versions of the popular medications. Additionally, Novo Nordisk recently cut its sales forecast, signaling a potential slowdown in the explosive growth previously seen in the weight-loss drug segment.
Adding to the pressure, former President Donald Trump has intensified his rhetoric against the pharmaceutical industry. He is demanding that drugmakers commit to a "most-favored nation policy" to lower U.S. drug prices to European levels and has threatened tariffs of up to 250% on pharmaceutical imports. These proposed tariffs aim to incentivize domestic drug production but could significantly impact the profit margins of companies heavily reliant on international supply chains.
Meanwhile, a high-stakes meeting between President Donald Trump and Russian President Vladimir Putin in Anchorage, Alaska, has seen a last-minute expansion. What was initially planned as a one-on-one discussion has now become a three-on-three format. President Trump is accompanied by Secretary of State Marco Rubio and Special Envoy Steve Witkoff for the bilateral talks. The meeting is focused on efforts to end the ongoing conflict in Ukraine.

Ed Liston is a senior contributing editor at TheStockMarketWatch.com. An active market watcher and investor, Ed guides an independent team of experienced analysts and writes for multiple stock trader publications.