{"id":52035,"date":"2025-08-15T09:38:17","date_gmt":"2025-08-15T13:38:17","guid":{"rendered":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/mixed-start-for-us-equities-as-industrial-production-dips-pfizer-drug-trial-fails\/52035\/"},"modified":"2025-08-15T09:38:17","modified_gmt":"2025-08-15T13:38:17","slug":"mixed-start-for-us-equities-as-industrial-production-dips-pfizer-drug-trial-fails","status":"publish","type":"post","link":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/mixed-start-for-us-equities-as-industrial-production-dips-pfizer-drug-trial-fails\/52035\/","title":{"rendered":"Mixed Start for US Equities as Industrial Production Dips; Pfizer Drug Trial Fails"},"content":{"rendered":"<h2>Key Takeaways<\/h2>\n<ul>\n<li><strong>US equities opened mixed<\/strong> on Friday, August 15, 2025, with the <strong><a href=\"https:\/\/stockmarketwatch.com\/markets\/dowjones\/today.aspx\" data-internallinksmanager029f6b8e52c=\"1\" title=\"Dow Jones Today\">Dow Jones<\/a> Industrial Average<\/strong> climbing significantly by <strong>260.62 points (0.58%)<\/strong> to <strong>45,171.88<\/strong>, while the <strong><a href=\"https:\/\/stockmarketwatch.com\/markets\/sp500\/\" data-internallinksmanager029f6b8e52c=\"3\" title=\"snp500 today\">S&amp;P 500<\/a><\/strong> saw a modest gain and the <strong>NASDAQ<\/strong> edged lower.<\/li>\n<li><strong>US industrial production unexpectedly declined by 0.1%<\/strong> in July, missing expectations, and <strong>capacity utilization also fell to 77.5%<\/strong>, signaling a potential slowdown in the manufacturing sector.<\/li>\n<li><strong>Pfizer (<a href=\"\/stock\/PFE\">PFE<\/a>) announced the failure of its Phase 3 trial<\/strong> for Inclacumab, a drug aimed at sickle cell disease, failing to meet its primary endpoint.<\/li>\n<li><strong>European gas costs have dropped to their lowest level in a year<\/strong>, providing some relief on energy prices, while <strong>German 30-year bond yields rose to 3.33%<\/strong>.<\/li>\n<\/ul>\n<h2>US Markets See Mixed Open<\/h2>\n<p>US stock markets opened with varied performance on Friday, August 15, 2025. The <strong>Dow Jones Industrial Average<\/strong> led the gains, rising <strong>260.62 points, or 0.58 percent<\/strong>, to reach <strong>45,171.88<\/strong> shortly after the market opened.<\/p>\n<p>In contrast, the <strong>S&amp;P 500<\/strong> posted a more modest increase, up <strong>6.27 points, or 0.10 percent<\/strong>, trading at <strong>6,474.81<\/strong>. The technology-heavy <strong>NASDAQ<\/strong> Composite, however, saw a slight decline, falling <strong>4.99 points, or 0.02 percent<\/strong>, to <strong>21,705.68<\/strong>.<\/p>\n<h2>Industrial Production and Capacity Utilization Decline in July<\/h2>\n<p>New economic data released for July 2025 indicates a contraction in US industrial activity. <strong>US Industrial Production (M\/M) fell by 0.1%<\/strong>, missing the estimated 0.0% and down from the previous month&#39;s 0.3% gain.<\/p>\n<p>Manufacturing production remained flat at <strong>0.0%<\/strong>, while specific sectors like motor vehicles &amp; parts, utilities, and mining all saw declines. Concurrently, the <strong>US Capacity Utilization Rate dropped to 77.5%<\/strong> in July, slightly below the estimated and previous rate of 77.6%.<\/p>\n<h2>Pfizer&#39;s Sickle Cell Drug Trial Fails<\/h2>\n<p>Pharmaceutical giant <strong>Pfizer (<a href=\"\/stock\/PFE\">PFE<\/a>)<\/strong> faced a setback with its experimental drug, Inclacumab. The company announced that its <strong>Phase 3 trial for Inclacumab<\/strong>, intended for the treatment of sickle cell disease, <strong>failed to achieve its main goal<\/strong>. This development could impact Pfizer&#39;s (<a href=\"\/stock\/PFE\">PFE<\/a>) pipeline in the rare disease segment.<\/p>\n<h2>European Gas Prices Hit One-Year Low as German Bond Yields Rise<\/h2>\n<p>In the commodities market, <strong>European gas costs have significantly decreased<\/strong>, reaching their <em>lowest level in a year<\/em>. This indicates a notable shift in energy prices across the continent.<\/p>\n<p>Meanwhile, the European bond market saw movement as <strong>German 30-Year Bonds continued to decline<\/strong>, with their <strong>yield rising by 7 basis points to 3.33%<\/strong>. This increase in yield suggests a decrease in the bond&#39;s price.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Key Takeaways US equities opened mixed on Friday, August 15, 2025, with the Dow Jones Industrial Average climbing significantly by [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":50383,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center 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