{"id":73490,"date":"2026-10-23T07:38:24","date_gmt":"2026-10-23T11:38:24","guid":{"rendered":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/american-express-beats-q3-estimates-bristol-myers-squibb-reports-breakthrough-oncology-data\/73490\/"},"modified":"2026-10-23T07:38:24","modified_gmt":"2026-10-23T11:38:24","slug":"american-express-beats-q3-estimates-bristol-myers-squibb-reports-breakthrough-oncology-data","status":"publish","type":"post","link":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/american-express-beats-q3-estimates-bristol-myers-squibb-reports-breakthrough-oncology-data\/73490\/","title":{"rendered":"American Express Beats Q3 Estimates; Bristol-Myers Squibb Reports Breakthrough Oncology Data"},"content":{"rendered":"<h2>Key Takeaways<\/h2>\n<ul>\n<li><strong>American Express (<a href=\"\/stock\/AXP\">AXP<\/a>)<\/strong> reported a significant <strong>Q3 earnings beat<\/strong> with <strong>Adjusted EPS of $4.68<\/strong>, well ahead of the <strong>$4.50<\/strong> projected by analysts, while raising its full-year guidance.<\/li>\n<li><strong>Bristol-Myers Squibb (<a href=\"\/stock\/BMY\">BMY<\/a>)<\/strong> announced that its Phase 3 study of <strong>iza-bren<\/strong> reduced the risk of disease progression or death by <strong>59%<\/strong> in patients with advanced breast cancer.<\/li>\n<li><strong>China<\/strong> issued a major position paper on <strong>outer space governance<\/strong>, calling for a legally binding treaty to prevent the weaponization of orbit and an international arms race.<\/li>\n<li><strong>CoreWeave (<a href=\"\/stock\/CRWV\">CRWV<\/a>)<\/strong> credit risk remains a focal point as credit default swaps price in a <strong>60% probability of default<\/strong>, despite verbal support from <a href=\"https:\/\/stockmarketwatch.com\/stock\/NVDA\" data-internallinksmanager029f6b8e52c=\"15\" title=\"stock: NVDA\">Nvidia<\/a> (<a href=\"\/stock\/NVDA\">NVDA<\/a>) CEO Jensen Huang.<\/li>\n<li><strong>US Midterm Election<\/strong> forecasts from <em>Sabato\u2019s Crystal Ball<\/em> suggest a &quot;knife-edge&quot; battle for the Senate, with Republican control increasingly under threat across seven key races.<\/li>\n<\/ul>\n<h2>Financial Markets and Corporate Earnings<\/h2>\n<p>American Express (<a href=\"\/stock\/AXP\">AXP<\/a>) delivered a robust third-quarter performance, reporting <strong>revenue of $20.06 billion<\/strong>, representing a <strong>9% year-over-year increase<\/strong>. Although revenue slightly missed the <strong>$20.12 billion<\/strong> consensus, the company\u2019s <strong>Adjusted EPS of $4.68<\/strong> comfortably cleared expectations. Strong credit quality was a highlight, as the <strong>provision for credit losses<\/strong> came in at <strong>$1 billion<\/strong>, lower than the <strong>$1.31 billion<\/strong> some analysts had feared. Consequently, the company raised its full-year <strong>Adjusted EPS guidance<\/strong> to a range of <strong>$17.60 to $17.90<\/strong>.<\/p>\n<p>In the technology sector, AI infrastructure provider <strong>CoreWeave (<a href=\"\/stock\/CRWV\">CRWV<\/a>)<\/strong> is facing intense market scrutiny. The cost of insuring the company&#39;s debt against default recently hit a record <strong>1,194.5 basis points<\/strong>, implying a <strong>60% chance of default<\/strong> within five years. While <a href=\"https:\/\/stockmarketwatch.com\/stock\/NVDA\" data-internallinksmanager029f6b8e52c=\"15\" title=\"stock: NVDA\">Nvidia<\/a> (<a href=\"\/stock\/NVDA\">NVDA<\/a>) CEO Jensen Huang has publicly defended the firm\u2019s financial strength, noting that its <strong>cost of capital is falling<\/strong>, the bond market remains on high alert with yields on some notes exceeding <strong>15%<\/strong>.<\/p>\n<h2>Healthcare and Biotechnology<\/h2>\n<p>Bristol-Myers Squibb (<a href=\"\/stock\/BMY\">BMY<\/a>) and partner SystImmune reported practice-changing data from the <strong>Phase 3 PANKU-Breast01<\/strong> study. The trial found that <strong>iza-bren<\/strong> (izalontamab brengitecan) delivered a median <strong>progression-free survival (PFS) of 8.2 months<\/strong>, more than double the <strong>4.0 months<\/strong> achieved by standard chemotherapy. This dual-targeting antibody-drug conjugate (ADC) has now demonstrated clinical benefit across <strong>five distinct tumor types<\/strong>, positioning it as a potential new standard of care for heavily pre-treated patients.<\/p>\n<h2>Global Policy and Geopolitics<\/h2>\n<p><strong>China<\/strong> has intensified its diplomatic push for space security, releasing a formal position paper on <strong>strengthening outer space governance<\/strong>. The document advocates for the principle that &quot;a war in outer space cannot be won and must not be fought,&quot; specifically targeting the deployment of on-orbit space control weapons. Domestically, the Chinese cabinet also signaled a shift in economic priorities, urging local governments to <strong>stabilize the number of new births<\/strong> and expand investment in the <strong>services sector<\/strong> to combat demographic decline.<\/p>\n<h2>2026 US Midterms Outlook<\/h2>\n<p>With the <strong>2026 US Midterm Elections<\/strong> just two weeks away, nonpartisan analysts at the University of Virginia\u2019s <em>Sabato\u2019s Crystal Ball<\/em> indicate that the House of Representatives appears likely to flip, while the <strong>Senate remains a toss-up<\/strong>. Managing editor Kyle Kondik highlighted that <strong>seven Senate races<\/strong> will ultimately decide control of the chamber. Markets are currently weighing three primary scenarios, ranging from a Republican hold to a Democratic sweep, with particular attention on a potential bipartisan move to <strong>reclaim tariff authority<\/strong> from the executive branch.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Key Takeaways American Express (AXP) reported a significant Q3 earnings beat with Adjusted EPS of $4.68, well ahead of the [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":50383,"comment_status":"","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"rank_math_schema_Article":[],"rank_math_focus_keyword":[],"rank_math_description":[],"financial_data_references":[],"stock_symbols_mentioned":[],"footnotes":""},"categories":[5012],"tags":[215,808,1268,4154,7213,7908,8715,13517,23411],"class_list":["post-73490","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-breaking-news","tag-bmy","tag-axp","tag-pfs","tag-crwv","tag-stockmarket","tag-earningsseason","tag-oncology","tag-adc","tag-midterms2026"],"_links":{"self":[{"href":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/wp-json\/wp\/v2\/posts\/73490","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/wp-json\/wp\/v2\/comments?post=73490"}],"version-history":[{"count":0,"href":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/wp-json\/wp\/v2\/posts\/73490\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/wp-json\/wp\/v2\/media\/50383"}],"wp:attachment":[{"href":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/wp-json\/wp\/v2\/media?parent=73490"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/wp-json\/wp\/v2\/categories?post=73490"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/wp-json\/wp\/v2\/tags?post=73490"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}