{"id":73755,"date":"2026-10-28T10:38:19","date_gmt":"2026-10-28T14:38:19","guid":{"rendered":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/eli-lilly-retatrutide-outperforms-ozempic-in-landmark-trial-fed-holds-rates-steady\/73755\/"},"modified":"2026-10-28T10:38:19","modified_gmt":"2026-10-28T14:38:19","slug":"eli-lilly-retatrutide-outperforms-ozempic-in-landmark-trial-fed-holds-rates-steady","status":"publish","type":"post","link":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/eli-lilly-retatrutide-outperforms-ozempic-in-landmark-trial-fed-holds-rates-steady\/73755\/","title":{"rendered":"Eli Lilly Retatrutide Outperforms Ozempic in Landmark Trial; Fed Holds Rates Steady"},"content":{"rendered":"<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_89 counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">Table of Contents<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 eztoc-toggle-hide-by-default' ><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"#\" data-href=\"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/eli-lilly-retatrutide-outperforms-ozempic-in-landmark-trial-fed-holds-rates-steady\/73755\/#Key_Takeaways\" >Key Takeaways<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"#\" data-href=\"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/eli-lilly-retatrutide-outperforms-ozempic-in-landmark-trial-fed-holds-rates-steady\/73755\/#Healthcare_Lillys_%22Triple-G%22_Dominates_Head-to-Head_Trial\" >Healthcare: Lilly&#39;s &quot;Triple-G&quot; Dominates Head-to-Head Trial<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"#\" data-href=\"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/eli-lilly-retatrutide-outperforms-ozempic-in-landmark-trial-fed-holds-rates-steady\/73755\/#Monetary_Policy_FOMC_and_the_%22Warsh%22_Press_Conference\" >Monetary Policy: FOMC and the &quot;Warsh&quot; Press Conference<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"#\" data-href=\"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/eli-lilly-retatrutide-outperforms-ozempic-in-landmark-trial-fed-holds-rates-steady\/73755\/#Energy_Infrastructure_Hormuz_Bypass_and_LNG_Outlook\" >Energy &amp; Infrastructure: Hormuz Bypass and LNG Outlook<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"#\" data-href=\"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/eli-lilly-retatrutide-outperforms-ozempic-in-landmark-trial-fed-holds-rates-steady\/73755\/#Global_Markets_UK_Fiscal_Headroom_and_Russian_Grain\" >Global Markets: UK Fiscal Headroom and Russian Grain<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"#\" data-href=\"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/eli-lilly-retatrutide-outperforms-ozempic-in-landmark-trial-fed-holds-rates-steady\/73755\/#Corporate_Briefs\" >Corporate Briefs<\/a><\/li><\/ul><\/nav><\/div>\n<h2><span class=\"ez-toc-section\" id=\"Key_Takeaways\"><\/span>Key Takeaways<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li><strong>Eli Lilly (<a href=\"\/stock\/LLY\">LLY<\/a>)<\/strong> reported Phase 3 trial results showing its experimental drug <strong>retatrutide<\/strong> achieved <strong>20-21% weight loss<\/strong>, more than doubling the <strong>9.4%<\/strong> achieved by <strong>Novo Nordisk\u2019s (<a href=\"\/stock\/NVO\">NVO<\/a>)<\/strong> Ozempic.<\/li>\n<li>The <strong>Federal Reserve<\/strong> is expected to keep interest rates unchanged in the <strong>3.75%\u20134% range<\/strong> today, with Chairman <strong>Kevin Warsh<\/strong> scheduled for a highly anticipated press conference at 2:30 p.m. ET.<\/li>\n<li><strong>ADNOC<\/strong> has informed clients that a new pipeline bypassing the <strong>Strait of Hormuz<\/strong> will be operational by <strong>early 2027<\/strong>, effectively doubling the UAE&#39;s export capacity to the Gulf of Oman.<\/li>\n<li><strong>UK Gilts<\/strong> rallied as 30-year yields fell to a day low of <strong>5.70%<\/strong> following the <strong>OBR\u2019s<\/strong> estimate of <strong>\u00a312.5 billion<\/strong> in pre-measures fiscal headroom for 2029-30.<\/li>\n<li><strong>Russia<\/strong> has authorized the departure of grain vessels from <strong>Azov Sea<\/strong> ports through the <strong>Kerch Strait<\/strong> for the first time since July, with permits valid through November 15.<\/li>\n<\/ul>\n<h2><span class=\"ez-toc-section\" id=\"Healthcare_Lillys_%22Triple-G%22_Dominates_Head-to-Head_Trial\"><\/span>Healthcare: Lilly&#39;s &quot;Triple-G&quot; Dominates Head-to-Head Trial<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>Eli Lilly (<a href=\"\/stock\/LLY\">LLY<\/a>) announced today that its next-generation obesity treatment, <strong>retatrutide<\/strong>, significantly outperformed <strong>Novo Nordisk\u2019s (<a href=\"\/stock\/NVO\">NVO<\/a>)<\/strong> Ozempic in the TRANSCEND-T2D-2 Phase 3 trial. Patients on retatrutide lost an average of <strong>44 to 47 pounds<\/strong> (up to 21% of body weight) over 80 weeks, compared to just <strong>21 pounds<\/strong> (9.4%) for those on the highest approved dose of Ozempic.<\/p>\n<p>The drug, nicknamed &quot;Triple-G&quot; for its activation of three hormone receptors (GLP-1, GIP, and glucagon), also showed superior blood sugar control, reducing <strong>A1C levels by 2.2%<\/strong> versus 1.8% for Ozempic. Lilly plans to seek <strong>FDA approval<\/strong> for the treatment in early 2027, potentially disrupting the current market leadership held by Novo Nordisk.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Monetary_Policy_FOMC_and_the_%22Warsh%22_Press_Conference\"><\/span>Monetary Policy: FOMC and the &quot;Warsh&quot; Press Conference<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The <strong>Federal Open Market Committee (FOMC)<\/strong> is concluding its two-day meeting today, with markets pricing in a <strong>90% probability<\/strong> that interest rates will remain steady. This marks the first meeting under Chairman <strong>Kevin Warsh<\/strong> just days before the U.S. midterm elections, placing intense scrutiny on his 2:30 p.m. ET press conference.<\/p>\n<p>Investors are looking for clues regarding a potential <strong>December rate hike<\/strong>, as recent inflation data remains &quot;sticky&quot; despite the current pause. The <a href=\"https:\/\/stockmarketwatch.com\/indices\/sp500\/today\" data-internallinksmanager029f6b8e52c=\"3\" title=\"snp500 today\">S&amp;P 500<\/a> has historically struggled on rate-decision days this year, and traders are watching for any hawkish signals that could push the <strong>EUR\/USD<\/strong> to fresh 17-month lows.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Energy_Infrastructure_Hormuz_Bypass_and_LNG_Outlook\"><\/span>Energy &amp; Infrastructure: Hormuz Bypass and LNG Outlook<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The Abu Dhabi National Oil Company (<strong>ADNOC<\/strong>) has confirmed that its <strong>West-East Pipeline<\/strong> project is now <strong>50% complete<\/strong> and on track for an early 2027 start. This infrastructure is critical for global energy security, as it allows the UAE to bypass the <strong>Strait of Hormuz<\/strong>, a chokepoint currently seeing significant disruption due to regional tensions.<\/p>\n<p>In related energy news, Baker Hughes (<a href=\"\/stock\/BKR\">BKR<\/a>) projected that global <strong>LNG capacity<\/strong> will reach <strong>800 million tonnes per annum<\/strong> by 2030. This growth is driven by a structural shift in European demand and ongoing infrastructure expansions in the Middle East and North America.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Global_Markets_UK_Fiscal_Headroom_and_Russian_Grain\"><\/span>Global Markets: UK Fiscal Headroom and Russian Grain<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<p>The UK Debt Management Office (<strong>DMO<\/strong>) announced a new <strong>Standing Repo Facility<\/strong> for T-bills to launch in January, aimed at boosting market liquidity. The facility will likely be priced at <strong>20 basis points below the Bank of England rate<\/strong>, providing a new safety valve for primary dealers.<\/p>\n<p>In Eastern Europe, the Kremlin indicated that <strong>trilateral talks<\/strong> between Russia, the U.S., and Ukraine could resume after November 4. Simultaneously, Russia has eased some maritime restrictions, allowing grain exports to resume from the <strong>Azov Sea<\/strong> via the Kerch Strait, providing a temporary reprieve for global agricultural markets.<\/p>\n<h2><span class=\"ez-toc-section\" id=\"Corporate_Briefs\"><\/span>Corporate Briefs<span class=\"ez-toc-section-end\"><\/span><\/h2>\n<ul>\n<li><strong>IBM (<a href=\"\/stock\/IBM\">IBM<\/a>)<\/strong> has extended its partnership with the <strong>US Open<\/strong>, serving as the official AI and Cloud partner through 2031.<\/li>\n<li><strong>Pakistan<\/strong> has reversed a long-standing policy, now allowing <strong>Taiwanese airlines<\/strong> to use its airspace, signaling a shift in regional aviation diplomacy.<\/li>\n<li><strong>UK 30-year Gilt yields<\/strong> hit a day low of <strong>5.70%<\/strong> as investors reacted to the latest <strong>Office for Budget Responsibility (OBR)<\/strong> fiscal forecasts.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Key Takeaways Eli Lilly (LLY) reported Phase 3 trial results showing its experimental drug retatrutide achieved 20-21% weight loss, more 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