{"id":74392,"date":"2026-11-09T11:08:34","date_gmt":"2026-11-09T15:08:34","guid":{"rendered":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/eli-lillys-foundayo-shines-in-sleep-apnea-trial-big-tech-rallies-on-analyst-upgrades\/74392\/"},"modified":"2026-11-09T11:08:34","modified_gmt":"2026-11-09T15:08:34","slug":"eli-lillys-foundayo-shines-in-sleep-apnea-trial-big-tech-rallies-on-analyst-upgrades","status":"publish","type":"post","link":"https:\/\/www2.stockmarketwatch.com\/stock-market-news\/eli-lillys-foundayo-shines-in-sleep-apnea-trial-big-tech-rallies-on-analyst-upgrades\/74392\/","title":{"rendered":"Eli Lilly\u2019s Foundayo Shines in Sleep Apnea Trial; Big Tech Rallies on Analyst Upgrades"},"content":{"rendered":"<h2>Key Takeaways<\/h2>\n<ul>\n<li><strong>Eli Lilly (<a href=\"\/stock\/LLY\">LLY<\/a>)<\/strong> reported that its oral obesity drug <strong>Foundayo<\/strong> (orforglipron) reduced sleep apnea severity by up to <strong>43.8%<\/strong> in a 52-week Phase 3 trial.<\/li>\n<li><strong>Amazon (<a href=\"\/stock\/AMZN\">AMZN<\/a>)<\/strong> and <strong>Meta Platforms (<a href=\"\/stock\/META\">META<\/a>)<\/strong> shares surged <strong>5.5%<\/strong> and <strong>4.5%<\/strong> respectively following bullish sentiment from <strong>JPMorgan<\/strong>, which named them top internet picks.<\/li>\n<li>Senator <strong>Chris Van Hollen<\/strong> has reportedly entered &quot;active listening mode&quot; regarding a potential challenge to <strong>Chuck Schumer<\/strong> for Senate Democratic leadership.<\/li>\n<li><strong>Alphabet (<a href=\"\/stock\/GOOGL\">GOOGL<\/a>)<\/strong> shares gained <strong>3.2%<\/strong> as the broader mega-cap tech sector rebounded, despite being removed from JPMorgan&#39;s Analyst Focus List in favor of Meta.<\/li>\n<\/ul>\n<h2>Eli Lilly\u2019s Foundayo Meets Primary Endpoints in Sleep Apnea Study<\/h2>\n<p><strong>Eli Lilly (<a href=\"\/stock\/LLY\">LLY<\/a>)<\/strong> announced breakthrough results from its <strong>ATTAIN-OSA<\/strong> Phase 3 clinical trial, demonstrating that its oral GLP-1 receptor agonist, <strong>Foundayo<\/strong>, significantly improves outcomes for patients with obstructive sleep apnea (OSA). At the 52-week mark, participants not using positive airway pressure (PAP) therapy saw a mean reduction of <strong>21.1 events per hour<\/strong> on the Apnea-Hypopnea Index (AHI), representing a <strong>43.8%<\/strong> improvement from baseline.<\/p>\n<p>The study, presented at the <strong>American Heart Association (AHA) Scientific Sessions 2026<\/strong>, also highlighted significant secondary benefits. Participants experienced an average weight loss of approximately <strong>11%<\/strong> and a reduction in systolic blood pressure by up to <strong>8.6 mmHg<\/strong>. Following these results, <strong>Eli Lilly (<a href=\"\/stock\/LLY\">LLY<\/a>)<\/strong> confirmed plans to submit <strong>Foundayo<\/strong> for FDA approval in the OSA indication by the end of 2026.<\/p>\n<h2>Big Tech Rallies as JPMorgan Shifts Focus to Meta and Amazon<\/h2>\n<p>Mega-cap technology stocks saw a significant boost on Monday, led by a <strong>5.5%<\/strong> jump in <strong>Amazon (<a href=\"\/stock\/AMZN\">AMZN<\/a>)<\/strong> and a <strong>4.5%<\/strong> rise in <strong>Meta Platforms (<a href=\"\/stock\/META\">META<\/a>)<\/strong>. The rally was largely attributed to <strong>JPMorgan<\/strong> updating its Analyst Focus List, where it identified Meta and Amazon as its preferred internet sector picks for the remainder of the year.<\/p>\n<p>While <strong>Alphabet (<a href=\"\/stock\/GOOGL\">GOOGL<\/a>)<\/strong> climbed <strong>3.2%<\/strong>, it was notably removed from JPMorgan\u2019s focus list. Analysts cited <strong>Meta\u2019s<\/strong> superior near-term earnings momentum and AI-driven advertising gains as the primary reason for the rotation. Despite the removal, the bank maintains an <em>Overweight<\/em> rating on Alphabet, noting its continued growth in cloud and AI infrastructure.<\/p>\n<h2>Leadership Shakeup Looms in the U.S. Senate<\/h2>\n<p>In the political sphere, Senator <strong>Chris Van Hollen<\/strong> (D-MD) is reportedly considering a run against Senate Minority Leader <strong>Chuck Schumer<\/strong>. According to sources familiar with his thinking, Van Hollen has received an &quot;outpouring of calls&quot; and is currently in an active listening phase regarding a leadership bid.<\/p>\n<p>Van Hollen, a leading progressive voice, has signaled that he requires specific commitments from <strong>Schumer<\/strong> regarding the party&#39;s legislative agenda before offering his support for another term. This development comes amid broader discussions within the Democratic caucus following the 2026 midterm elections, where some members have called for a &quot;new generation&quot; of leadership.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Key Takeaways Eli Lilly (LLY) reported that its oral obesity drug Foundayo (orforglipron) reduced sleep apnea severity by up to 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